Since the inaugural APIC-ADVA Summit on Infectious Diseases and Immunization in 2023, the world continues to face a multitude of crises ranging from climate change, geopolitical upheavals, social and political polarization, humanitarian emergencies and the continued, evolving threat of pandemics of infectious diseases. In recent times, concern has been mounting for epidemic threats posed by mpox, avian influenza, a resurgence of polio and malaria, continued evolution of SARS-CoV-2, and increasing numbers of cholera outbreaks. It thus seems timely to convene the Second APIC-ADVA Summit on Infectious Diseases and Immunization in Singapore from February 11-13, 2025 to deliberate our responses to these looming threats to societies worldwide, especially in the Asia-Pacific region.

Beyond considering scientific advances in understanding pathogen biology and epidemiology, and advances in vaccine development, the Summit will provide a unique platform to broaden the discourse to include the impacts of climate change, major updates of relevant international health agreements and regulations, vaccine security, and the importance of evidence-informed policies. It will also highlight the need to overcome the misinformation and disinformation so prevalent in the world today, engage communities, and harness insights from behavioural and implementation sciences-all towards effective and equitable deployment of vaccines and other needed interventions to mitigate epidemic threats posed by infectious diseases. Underpinning all of the above and needed now, more than ever, is global solidarity and cooperation between key stakeholders at the global, regional and national levels to be prepared and respond collectively to these existential threats to humanity.

The Summit will be hosted by the Asia-Pacific Immunization Coalition (APIC), Asia Dengue Voice & Action (ADVA) group, and the Centre for Behavioural and Implementation Science Interventions (BISI) at the Yong Loo Lin School of Medicine, National University of Singapore. It will feature prominent and high-level speakers representing scientists, policy makers, and implementers from the region and from international organizations. We hope to welcome you in Singapore from February 11-13, 2025 to participate and contribute to the success of the Second APIC-ADVA Summit on Infectious Diseases and Immunization!